Efficacy of Triamcinolone in Treatment of Keloid
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Abstract
Introduction
Keloids are well known for recurrence. There is no standardized regimen for the treatment of keloids. Many different treatment modalities such as surgical excision, intralesional corticosteroids, radiotherapy, and pressure earrings have been used for keloids. Surgical excision alone may result in recurrence rate of 40%-100%. This study was conducted to evaluate the efficacy of triamcinolone in preventing recurrence of Keloid.
Materials and Methods
Of the 40 patients who underwent excision of keloid at a tertiary care centre, surgery alone was performed in 20 patients and surgery with post operative intra-lesional triamcinolone injection was given weekly interval for 6 weeks in another 20 patients. Patients were followed up for the period of 2 years
Results
Recurrence was found in 5 patients who underwent excision alone and there was no recurrence among patients who received post operative intra-lesional triamcinolone.
Conclusion
Multi-modality treatment is better to prevent recurrence of Keloid.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
References
Guo L, Xu K, Yan H, Feng H, Chai L, Xu G. Expression Profile of Long Noncoding RNAs in Human Earlobe Keloids: A Microarray Analysis. Biomed Res Int. 2016; 1:1-4
Pierce HE. Keloids: enigma of the plastic surgeon. Journal of National Medical Association. 1979; 71(12):1177-80
Wong TS, Li JZ, Chen S, Chan JY, Gao W. The efficacy of triamcinolone acetonide in keloid treatment: A systematic review and meta-analysis. Front Med (Lausanne). 2016; 3:71
Metts J. Common complications of body piercing. West J Med. 2002;176(2):85-6
Sand M, Sand D, Boorboor P, Mann B, Altmeyer P, Hoffmann K, Bechara FG. Combination of surgical excision and custom designed silicon pressure splint therapy for keloids on the helical rim. Head Face Med. 2007; 12(3):14
Bashir MM, Ahmad H, Yousaf N, Khan FA. Comparison of single intra operative versus an intra operative and two post operative injections of the triamcinolone after wedge excision of keloids of helix. Journal of Pakistan medical association. 2015; 65(7):737-41.