A Rare Case of Childhood Lipoblastoma presenting as Tongue Mass

Main Article Content

Anand V
Aishwarya Anand
Manaswini Ramachandra
Sridurga Janarthanan

Abstract

Introduction


Lipoblastoma is a rare benign tumour arising from embryonic white fat been commonly noted in limbs and trunk, but tongue involvement is rare and has not yet been reported.


Case Report


A child with tongue lipoblastoma is reported, whose imaging reported an encapsulated, well-delineated, fat-containing tumour. Surgical excision was performed with no post-operative morbidities. 


Discussion


Lipoblastoma is an uncommon childhood tumour, which rarely affects the tongue. It presents as a progressive painless swelling, rarely causing any symptom. MRI is helpful to assess the precise location and extent of the lesion. Although the ratio of fat to myxocollagenous tissue in the tumour is variable, the diagnosis can be suggested in most cases based on the imaging characteristics. Recommended treatment is complete surgical excision and confirmation of diagnosis by histopathological examination.

Article Details

How to Cite
1.
V A, Anand A, Ramachandra M, Janarthanan S. A Rare Case of Childhood Lipoblastoma presenting as Tongue Mass. BJOHNS [Internet]. 2021Jun.3 [cited 2024Dec.3];29(1):113-7. Available from: https://bjohns.in/journal3/index.php/bjohns/article/view/403
Section
Case report

References

Miller GG, Yanchar NL, Magee JF, Blair GK. Lipob- lastoma and liposarcoma in children: an analysis of 9 cases and a review of the literature. Can J Surg. 1998; 41: 455-8

Sakaida M, Shimizu T, Kishioka C, Majima Y. Lipoblastoma of the neck: a case report and literature review. Am J Otolaryngol. 2004; 25: 266-9

Papaioannou G, Sebire N, McHugh K. Imaging of the unusual pediatric ‘blastomas’ Cancer Imaging 2009; 9:1-11

Jaffè RH. Recurred lipomatoustumors of the groin: liposarcoma and lipomapseudomyxomatodes. Arch Pathol. 1926; 1:381-7

Vellios F, Baez J, Shumacker HB. Lipoblastomatosis: a tumor of fetal fat different from hibernoma. Report of a case, with observations of the embryogenesis of human adipose tissue. Am J Pathol. 1958; 34:1149-59

McVay MR, Keller JE, Wagner CW, Jackson RJ, Smith SD. Surgical management of lipoblastoma. J Pediatr Surg. 2006; 41:1067-71

Pham N, Poirier B, Fuller S, et al. Pediatric lipoblastoma in the head and neck: a systematic review of 48 reported cases. Int J Pediatr Otorhinolaryngol. 2010; 74:723-8

Murphey M, Carroll J, Flemming D, et al. From the archive from AFIP. Benign musculoskeletal lipomatous lesions. Radiographics 2004; 24:1433-66

Calhoun KH, Clark WD, Jones JD. Parotid lipoblastoma in an infant. Int J Pediatr Otorhinolaryngol. 1987; 14(1):41-4

Rasmussen IS, Kirkegaard J, Kaasbol M. Intermittent airway obstruction in a child caused by a cervical lipoblastoma. Acta Anaesthesiol Scand. 1997; 41(7):945

Farrugia MK, Fearne C. Benign lipoblastoma arising in the neck. Pediatr Surg Int. 1998; 13(2-3):213-4

DePasquale K, Deschler DG. First report of a lipoblastoma of the parapharyngeal space. Ear Nose Throat J. 2002; 81(8):564-8

Navarro OM, Laffan EE, Ngan BY. Pediatric soft-tissue tumors and pseudotumors: MRI imaging features with pathologic correlation. Radiographics 2009; 29:887-906

Castellote A, Vazquez E, Vera J, et al. Cervicothoracic lesions in infants and children. Radiographics 1999; 19:583-600

Miller GG, Yanchar NL, Magee JF, Blair GK. Tumor karyotype differentiates lipoblastoma from liposarcoma. J Pediatr Surg. 1997; 32: 1771-2

de Saint Aubain Somerhausen N, Coindre JM, Debiec-Rychter M, et al. Lipoblastoma in adolescents and young adults: report of six cases with FISH analysis. Histopathology 2008; 52:294-8

Hibbard MK, Kozakewich HP, Dal Cin P, et al. PLAG1 fusion oncogenes in lipoblastoma. Cancer Res. 2000;60: 4869-72

Tallini G, Akerman M, Dal Cin P, et al. Combined morphologic and karyotypic study of 28 myxoidliposarcomas. Implications for a revised morphologic typing (a report from the CHAMP Group) Am J Surg Pathol. 1996; 20:1047-55

Sciot R, De Wever I, Debiec-Rychter M. Lipoblastoma in a 23-year-old male:

distinction from atypical lipomatous tumor using cytogenetic and fluorescence in situ hybridization analysis. Virchows Arch. 2003; 442:468-71

Jung S, Chang P, Luo C, Huang C, Lai J, Hsueh C. Lipoblastoma/ lipoblastomatosis: a clinicopathologic study of 16 cases in Taiwan. Pediatr Surg Int. 2005; 21: 809-12

Reiseter T, Nordshus T, Borthne A, Roald B, et al. Lipoblastoma: MRI appearances of a rare paediatric soft tissue tumour. Pediatr Radiol. 1999; 29(7):542-5. doi: 10.1007/s002470050641

Bruyeer E, Lemmerling M, Poorten VV, et al. Paediatric lip- oblastoma in the head and neck: three cases and review of literature. Cancer Imaging 2012; 12:484e7.