Paediatric Para-Meningeal Alveolar Rhabdomyosarcoma in the Nasal Cavity
Article Sidebar
Main Article Content
Abstract
ABSTRACT
Introduction
Rhabdomyosarcoma is the second most common malignant soft tissue tumor, which is of skeletal muscle in origin. Alveolar subtype of rhabdomyosarcoma is commonly seen in 10-25 years of age. We present a rare case of alveolar rhabdomyosarcoma in a one year old child.
Case report
A one-year-old boy presented with swelling and nasal discharge in the left nasal cavity of two months duration. Examination showed a smooth pink-coloured mass in the left nasal cavity arising from the lateral wall. Fine needle aspiration cytology, biopsy, imaging studies and immunohistochemistry were done and a diagnosis of alveolar rhabdomyosarcoma confirmed. Treatment was done by chemoradiation.
Discussion
Biopsy and immunohistochemistry are the gold standard investigations for rhabdomyosarcoma. It requires a multimodal treatment approach including surgery, chemotherapy, and radiotherapy.
Keywords
Rhabdomyosarcoma; Paediatric malignancy; Para meningeal; Alveolar; Nasal cavity
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
References
Chigurupati R, Alfatooni A, Myall RW, Hawkins D, Oda D. Orofacial rhabdomyosarcoma in neonates and young children: A review of literature and management of four cases. Oral Oncol 2002; 38:508-15
Stout AP. Rhabdomyosarcoma of the skeletal muscles. Ann Surg.1946.123:447-32066
Sanghvi S, Misra P, Patel NR, Kalyoussef E, Baredes S, Eloy JA {2013), incidence trends a11d long-term survival analysis of sinonasal rhabdomyosarcoma. Am J Otolaryrigol. 34:682- 9.
Duraes GV, Jham BC, Mesquita AT, dos Santos CR, Miranda JL. Oral embryonal rhabdomyosarcoma in a child: A case report with immunohistochemical analysis. Oral Oncol Extra. 2006; 42:1058
Lawrence W, Jr, Hays DM, Moon TE: Lymphatic metastasis with childhood rhabdomyosarcoma, Cancer.1977; 39(2):556–559
D.D.D. Brad Neville, Carl Allen, Angela ChiOral and maxillofacial pathology(fourth ed.), Saunders (2015)
S.M. Anwar Sadat, Mushfiq Hassan Shaikh, Md Badruddoza,Rhabdomyosarcoma of a 7 year-old girl from Bangladesh: A case report with review of literature,
Oral and Maxillofacial Surgery Cases,Volume 6, Issue 4,2020
Turner JH, Richmon JD: Head and neck rhabdomyosarcoma: a critical analysis of population-based incidence and survival data, Otolaryngology Head Neck Surgery.2010;145(6):967–973
Szablewski V, Neuville A, Terrier P, Laé M, Schaub R. Garrel R, et al. (2015). Adult sinonasal soft tissue sarcoma: analysis of 48 cases from the French Sarcoma Group database. Laryngoscope 125:615-23
Kumar S, Perlman E, Harris CA, RaffdM and Tsokos M: Myogenin is a specific marker for rhabdomyosarcoma: An immunohistochemical study in paraffin-embedded tissues. Mod Pathol. 2000;13:988–993
Cessna MH, Zhou H, Perkins SL, Tripp SR, Layfield L, Daines C, and Coffin CM: Are myogenin and MyoD1 expression specific for rhabdomyosarcoma? A study of 150 cases, with emphasis on spindle cell mimics. Am J Surg Pathol. 25:1150–1157
Thompson CF, Kim BJ, Lai C, Grogan T, ElashoffD, SI John MA, et al. (2013). Sinonasal rhabdomyosarcoma: prognostic factors and treatment outcomes. lnt Forum Allergy Rhinol. 3:678-83
Wurm J, Constantinidis J, Grabenbauer GG, lro H (2005). Rhabdornyosarcomas of the nose and paranasal sínuses: treatment results in 15 cases. otolaryngol Head Neck Surg. 133:42-50.