Differential Diagnosis of Lateral Neck Masses A Case Series with Uncommon Presentations
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Abstract
Introduction: The neck and parapharyngeal space are one of the most vital regions in the body, encompassing multiple major blood vessels, nerves, spine and the airway itself. Lateral neck masses that present to an ENT practitioner may not only include a wide variety of differentials, but may present as emergencies in case of an airway compromise. In such situations, decision making and arriving at the diagnosis becomes important not only from a curative perspective but also from a lifesaving one. Here we discuss a few cases of lateral neck masses that had presented to us with unusual presentation or had a rare diagnosis, along with the line of management that was followed.
Cases: We present a case of a giant pleomorphic adenoma presenting with stridor, an adult onset cystic hygroma, a schwannoma presenting with dyspnea, an isolated infiltrating lipoma and 2 other cases of schwannoma.
Conclusion: Tumours of the neck and parapharyngeal region have a wide variety as this region contains almost every kind of tissue. Diagnosis of any lesion should be done with caution, using the appropriate history, examination and investigative tools available. Not only the common presentation, but also outliers and uncommon presentations of common tumours should be kept in mind.
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References
Krishnan S. Tumours of the parapharyngeal space. In Head & Neck Surgery Plastic Surgery 2018 Aug 21 (pp. 157-170). CRC Press
Riffat F, Dwivedi RC, Palme C, Fish B, Jani P. A systematic review of 1143 parapharyngeal space tumors reported over 20 years. Oral oncology. 2014 May 1;50(5):421-30
Abd El-Monem MH, Gaafar AH, Magdy EA. Lipomas of the head and neck: presentation variability and diagnostic work-up. The Journal of Laryngology & Otology. 2006 Jan;120(1):47-55
Mahenthiralingam E, Urban TA, Goldberg JB. The multifarious, multireplicon Burkholderia cepacia complex. Nature Reviews Microbiology. 2005 Feb;3(2):144-56
Eisele DW, Richmon JD. Contemporary evaluation and management of parapharyngeal space neoplasms. The Journal of Laryngology & Otology. 2013 Jun;127(6):550-5
Gupta A, Chazen JL, Phillips CD. Imaging evaluation of the parapharyngeal space. Otolaryngologic clinics of North America. 2012 Dec 1;45(6):1223-32
Arnason T, Hart RD, Taylor SM, Trites JR, Nasser JG, Bullock MJ. Diagnostic accuracy and safety of fine‐needle aspiration biopsy of the parapharyngeal space. Diagnostic Cytopathology. 2012 Feb;40(2):118-23
Farrag TY, Lin FR, Koch WM, Califano JA, Cummings CW, Farinola MA, Tufano RP. The role of pre-operative CT-guided FNAB for parapharyngeal space tumors. Otolaryngology—Head and Neck Surgery. 2007 Mar;136(3):411-4
Oliai BR, Sheth S, Burroughs FH, Ali SZ. “Parapharyngeal space” tumors: A cytopathological study of 24 cases on fine‐needle aspiration. Diagnostic cytopathology. 2005 Jan;32(1):11-5
Battaglia P, Turri-Zanoni M, Dallan I, Gallo S, Sica E, Padoan G, Castelnuovo P. Endoscopic endonasal transpterygoid transmaxillary approach to the infratemporal and upper parapharyngeal tumors. Otolaryngology--Head and Neck Surgery. 2014 Apr;150(4):696-702
Chen WL, Wang YY, Zhang DM, Huang ZQ. Endoscopy-assisted transoral resection of large benign parapharyngeal space tumors. British Journal of Oral and Maxillofacial Surgery. 2014 Dec 1;52(10):970-3
O’Malley Jr BW, Quon H, Leonhardt FD, Chalian AA, Weinstein GS. Transoral robotic surgery for parapharyngeal space tumors. Orl. 2010;72(6):332-6
Califano J, Eisele DW. Benign salivary gland neoplasms. Otolaryngol Clin North Am, 1999; 32:861-73
Jain S, Hasan S, Vyas N, Shah N, Dalal S. Pleomorphic adenoma of the parotid gland: report of a case with review of literature. Ethiopian journal of health sciences. 2015;25(2):189-94
Mendenhall WM, Mendenhall CM, Werning JW, Malyapa RS, Mendenhall NP. Salivary gland pleomorphic adenoma. American journal of clinical oncology. 2008 Feb 1;31(1):95-9
Bozza F, Vigili MG, Ruscito P, Marzetti A, Marzetti F. Surgical management of parapharyngeal space tumours: results of 10-year follow-up. Acta Otorhinolaryngologica Italica. 2009 Feb;29(1):10
Miceli A, Stewart KM. Lymphangioma. InStatPearls [Internet] 2021 Aug 12. StatPearls Publishing
Mathew M, Dil SK. Adult lymphangioma—a rare entity: a report of two cases. Turk Patoloji Derg. 2012 Jan 1;28(1):80-2
Wang J, Yang Y, Guo J, Yao Y, Dong L, Mou Y, Zhang Y, Song X. Cervical lymphangioma in adults: A report of seven cases and review of the literature. Laryngoscope Investigative Otolaryngology. 2022 Apr 22
Graham ME, Perkins JA, Grimmer JF. 25 Vascular Anomalies of the Head and Neck. Cummings Pediatric Otolaryngology E-Book. 2021 Aug 25:344
Ansari I, Ansari A, Graison AA, Patil AJ, Joshi H. Head and neck schwannomas: A surgical challenge—A series of 5 cases. Case Reports in Otolaryngology. 2018 Mar 4;2018
Gibber MJ, Zevallos JP, Urken ML. Enucleation of vagal nerve schwannoma using intraoperative nerve monitoring. The Laryngoscope. 2012 Apr;122(4):790-2
Torossian JM, Beziat JL, Abou Chebel N, Devouassoux-Shisheboran M, Fischer G. Extracranial cephalic schwannomas: a series of 15 patients. The Journal of Craniofacial Surgery. 1999 Sep 1;10(5):389-94
Moumoulidis I, Durvasula P, Jani P. Well-circumscribed intramuscular lipoma of the sternocleidomastoid muscle. Auris Nasus Larynx. 2004 Sep 1;31(3):283-5
McTighe S, Chernev I. Intramuscular lipoma: a review of the literature. Orthopedic reviews. 2014 Oct 10;6(4).