Intralesional Sclerotherapy with Polidocanol in the Management of Head and Neck Vascular Lesions

Main Article Content

Arindam Das
Anindita Sengupta
Debashis Ghosh
Deepjoy Bose
Subhadip Dhara
Arunabha Sengupta

Abstract

Introduction


Vascular lesions (Hemangioma or vascular malformation) in the head and neck region are quite common and need therapeutic intervention if they become symptomatic or cosmetically unacceptable. Different therapeutic modalities including cryotherapy, corticosteroids, laser therapy, sclerotherapy, surgery and/or embolization are available. Advances in laser surgery as well as sclerotherapy techniques have improved our ability to treat extensive lesions. Surgical excision sometimes becomes very difficult due to massive per-operative bleeding and proximity to major neurovascular structures. In this study we have tried to find a simpler, easily available, safe and cost-effective therapy to treat these vascular lesions.


Materials and Method        


A pilot case study was conducted in a tertiary care hospital in Kolkata for a period of one year. Polidocanol was selected as the sclerosing agent for treatment of head and neck vascular lesions for its safety and its local anesthetic effect. 3% Polidocanol was injected in 20 lesions.


Result


20 patients with head and neck vascular lesions treated with polidocanol sclerotherapy were followed up for 12 months. The study included 20 patients (12 female and 8 male) with mean age 20.3 years (range 6-62 years). Of these 20 patients 14 had 90% to 100% result and in 6 patients we obtained only mild improvement.


Discussion


Sclerotherapy is now becoming the first choice of treatment in head and neck vascular lesions. Polidocanol is a mixture of 5% ethyl alcohol and 95% hydroxypolyethoxydodecane, the detergent action of which induces a rapid overhydration of endothelial cells, leading to vascular injury and regression of vascular lesions. As the same time it is a local anesthetic, so treatment is painless.


Conclusion


It is a less invasive, cost effective, painless OPD based management for head and neck vascular lesions having good functional and aesthetic outcome.

Article Details

How to Cite
1.
Das A, Sengupta A, Ghosh D, Bose D, Dhara S, Sengupta A. Intralesional Sclerotherapy with Polidocanol in the Management of Head and Neck Vascular Lesions. BJOHNS [Internet]. 2016Dec.18 [cited 2024May9];24(3):136-40. Available from: https://bjohns.in/journal3/index.php/bjohns/article/view/131
Section
Main article
Author Biographies

Arindam Das, Kothari Medical Centre.

ENT Consultant.

Anindita Sengupta, IPGME&R & SSKM Hospital

Senior Resident

Debashis Ghosh, IPGME&R & SSKM Hospital

Assistant Professor

Deepjoy Bose, Kothari Medical Centre.

ENT Consultant

Subhadip Dhara, IPGME&R & SSKM Hospital

Senior Resident

Arunabha Sengupta, IPGME&R & SSKM Hospital

Professor & Head, Dept. of ENT

References

Nosher JL, Murillo PG, Liszewski M, Gendel VG, Gribbin CE. Vascular anomalies: A pictorial review of nomenclature, diagnosis and treatment. World J Radiol. 2014; 6(9): 677-92

Mulliken JB, Glowacki J. Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg. 1982; 69(3):412–422. doi: 10.1097/00006534-198203000-00002

Buckmiller LM, Richter GT, Suen JY. Diagnosis and management of hemangiomas and vascular malformations of the head and neck. Oral Diseases 2010; 16(5): 405-18

Waner M, Suent Y, Dinehat S. Treatment of hemangioma of the head and neck. Laryngoscope 1992; 10:1123–1132. doi: 10.1288/00005537-199210000-00007

Uehara S, Osuga K, Yoneda A, Oue T, Yamanaka H, Fukuzawa M. Intralesional sclerotherapy for subcutaneous venous malformations in children. Pediatr Surg Int. 2009; 25:709-13

Blaise S, Charavin-Cocuzza M, Riom H, Brix M, Seinturier C, Diamand JM, Gachet G, Carpentier PH. Treatment of low-flow vascular malformations by ultrasound-guided sclerotherapy with polidocanol foam: 24 cases and literature review. Eur J Vasc Endovasc Surg. 2011; 41:412-7

Lorimier A. Sclerotherapy for venous malformations. J Pediatr Surg. 2003; 30:188-95. doi: 10.1016/0022-3468(95)90558-8

Govrin-Yehudain J, Moscona AR, Calderon N, Hirshowitz B. Treatment of hemangioma by sclerosing agents: an experimental and clinical study. Ann Plast Surg. 1987; 18:465-9. doi: 10.1097/00000637-198706000-00001

Minkow B, Laufer D, Gutman D. Treatment of oral hemangioma with local sclerosing agents. Int J Oral Surg. 1979; 8:18-21. doi: 10.1016/S0300-9785(79)80034-4

Hyodoh H, Hori M, Akiba H, Tamakawa M, Hyodoh K, Hareyama M. Periphral vascular malformations: imaging, treatment approaches and therapeutic issues. Radiographics 2005; 25(Suppl 1):S159-72. doi: 10.1148/rg.25si055509

Mimura H, Kanazawa S, Yasui K, Fujiwara H, Hyodo T, Mukai T, Dendo S, et al. Percutaneous sclerotherapy for venous malformations using polidocanol under fluoroscopy. Acta Med Okayama 2003; 57: 227-34

Jain R, Bandhu S, Sawhney S and Mittal R. Sonographically guided percutaneous sclerosis using 1% polidocanol in the treatment of vascular malformations. J Clin Ultrasound 2002; 30:416-23

Grover C, Arora P, Kedar A, Pal P, Lal B. Combination of oral corticosteroids and Polidocanolsclerotherapy in the management infantile haemangiomas. Dermatol Surg. 2010; 36:2030–6

Nishikawa M, Sakamoto K, Hidaka M, Yamashita A, Yamamoto G. Venous malformation of the tongue in a child treated by sclerotherapy with ethanolamine oleate: a case report. J Pediatr Surg. 2006; 41:599-600

Marrocco-Trischitta MM, Nicodemi EM, Stillo F. Sclerotherapy for venous malformations of the glans penis. Urology 2001; 57:310-3

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