Effect of Intratympanic Dexamethasone in Idiopathic Sudden Sensorineural Hearing Loss
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Abstract
Introduction
Oral steroids currently represent the standard treatment for idiopathic sudden sensorineural hearing loss The aim of this study is to assess the effectiveness of intratympanic dexamethasone injection for treating ‘Idiopathic sudden sensori-neural hearing loss’ (ISSNHL) not improved with conventional oral steroid.
Materials and Methods
A prospective study was conducted on 30 patients refractory to oral steroid therapy between June 2017 to May 2018. ‘Intratympanic dexamethasone injection’ (ITDI) was given every week for 3 consecutive weeks. Hearing was assessed by performing pure tone audiogram before every ITDI and also 1 week after the completion of treatment.
Results
Hearing improvement was found in 19 out of the 30 cases (63.3%).
Conclusions
Intratympanic dexamethasone significantly improves the prognosis of ISSNHL and is a safe, inexpensive and effective treatment.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
References
Tony N, Catherine R. Idiopathic sudden sensorineural hearing loss. In: John CW, Raymond WC, editors. Scott-Brown's Otorhinolaryngology, Head and Neck Surgery. Eighth ed, Taylor & Francis Group, LLC, 2018, 739-47
Anyah A, Mistry D, Kevern E, et al. Idiopathic Sudden Sensorineural Hearing Loss: Average Time Elapsed Before Presentation to the Otolaryngologist and Effectiveness of Oral and/or Intratympanic Steroids in Late Presentations. Cureus 2017; 9(12): e1945. DOI 10.7759/cureus.1945
Haynes DS, O’Malley M, Cohen S, Watford K, Labadie RF. Intratympanic Dexamethasone for Sudden Sensorineural Hearing Loss After Failure of Systemic Therapy. Laryngoscope 2007, 117:3-15
Belhassen S, Saliba I. Intratympanic Steroid injection as a salvage treatment for Sudden Sensorineural Hearing Loss. J Laryngol Otol. 2014; 1-6.
Wilson WR, Byl FM, Laird N. The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A doubleblind clinical study. Archives of Otolaryngology 1980;106(12):772–6
Chen WT, Lee JW, Yuan CH, Chen RF. Oral steroid treatment for idiopathic sudden sensorineural hearing loss. Saudi Med J. 2015; 36(3):291-6
Swamy KM, Arati G. Effect of intratympanic dexamethasone injection in sudden idiopathic sensorineural hearing loss. International Journal of Otorhinolaryngology and Head and Neck Surgery 2016 Oct; 2(4):258-62
Hyun JS. Intratympanic Steroid Injection in Tinnitus Management. Hanyang Med Rev. 2016; 36:125-30
Marx M, Younes E, Chandrasekhar SS, Ito J, et al. International consensus (ICON) on treatment of sudden sensorineural hearing loss. European Annals of Otorhinolaryngology, Head and Neck diseases 2018; 135: S23-S28
Steven DR, Robert D, Karen JD. Idiopathic sudden sensorineural hearing loss. In: Ashley W, James BS, editors. Ballengers Otorhinolaryngology: Head and neck surgery.18th ed. People's medical publishing house-USA, 2016, 1035-47
Sergey K, Arusyak A, Alexandr G, Edgar A, Alexandra K. Intratympanic Steroids for Sudden Sensorineural Hearing Loss. Int. Adv. Otol. 2011; 7:(3) 323-32
Zhao H, Zhang TY, Jing JH, Fu YY, Luo JN. Prognostic factors for patients with the idiopathic sudden sensorineural hearing loss [in Chineese]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2008; 43:660-4
Banerjee A, Parnes LS. Intratympanic corticosteroids for sudden idiopathic sensorineural hearing loss. Otol Neurotol 2005;26:878–81
Rong-rong L, Ji-chuan C, Changyou J. Sudden sensorineural hearing loss treated with intratympanic dexamethasone injection. Journal of Otology 2010; 5(1):4-7
Rauch SD. Intratympanic steroids for sensorineural hearing loss. Otolaryngol Clin North Am. 2004; 37:1061-74.